Kerecis – Overview

In the internationally expanding cellular therapy and infection prevention industries, Kerecis is a leader in the use of fish skin and fatty acids.

The fatty-acid-rich intact fish skin of Kerecis protects the tissues of the body and helps it to regenerate tissues. The sprayable topical and oral fatty-acid formulations of Kerecis protect the body from bacterial and viral infections.

Their drugs are used to treat acute and chronic wounds, including diabetic, venous, trauma, and surgical wounds, as well as burns and other complex wounds. Treatment with Kerecis has helped thousands of patients of all incomes, cultures, and races.

Fish skin comes from wild Atlantic cod, captured in pristine Icelandic waters from sustainable fish stock and processed using renewable energy.

Why Kerecis ?

When intact fish skin is rich in naturally occurring Omega3 polyunsaturated fatty acids, then it is termed Kerecis Omega3. The substance recruits the cells of the body when grafted onto damaged human tissue, such as a burn or a diabetic wound, and is gradually converted into living tissue.

Kerecis Omega3 provides better economic and clinical efficiency as well as decreased risk of disease transmission and no cultural limitations on use compared to mammalian-based skin replacements.

Other tissue-transplantation products are based on human and porcine tissues. Owing to heavy processing, these are not perfect replacements.

Primary technical advantages

• No religious boundaries or cultural restrictions on accepting patients.
• Simpler to use with thicker and larger sheets to avoid multi-layer grafting.
• Bio-compatible and Non-allergenic.
• No possible danger of transfer of disease.
• Increased vascularization and proliferation of cell
• Enhanced infection control
• Flexible absorption rate into the encircling tissue.

How do fish skin grafts help?

Intact fish skin rich in naturally occurring Omega3 polyunsaturated fatty acids is Kerecis Omega3. The substance recruits the body’s cells and is gradually transformed into living tissue when grafted onto damaged human tissue, such as a burn or a diabetic wound.

It has been shown that fish skin is similar to human skin in structure than anti-viral-processed skin substitutes. Fish skin is only minimally treated, maintaining its structure and components, so there is no chance of disease transmission. The fish skin was favorably compared to mammalian skin substitutes in a double-blind, comparable, randomized, and controlled clinical trial.

The application incorporates the skin reconstruction in:

• Chronic wounds
• Burn
• Hernia repair
• Oral wounds
• Dura mater
• Breast

Other tissue-transplantation products are based on human and porcine tissues. The risk of disease transmission to humans from mammalian tissue is non-existent from Atlantic cod to humans. The FDA has specific criteria for farm animal tissues, including viral inactivation techniques requiring treatment with detergents that strip tissue lipids and denature the native structure, leaving only the most insoluble collagens behind. Products such as skin and dehydrated human amnion/chorion membrane from human tissues require intensive use of antibiotics to reduce the bioburden. Acellular fish skin grafting is not subject to this harsh application, leaving the product with its associated benefits more naturally intact.

The fish are captured on the northwest coast of Iceland in the pristine waters of the North Atlantic Ocean off the township of Isafjordur. To guarantee product quality, every batch of raw materials is monitored. Using a proprietary method that preserves its structure and lipid composition, fish skin is processed.

European regulatory and FDA approved

The FDA and European regulatory authorities have approved Kerecis Omega3 Wound for wound healing. The substance is currently being registered with various regulatory authorities around the world.

Kerecis has demonstrated its ability to manufacture lipid-containing tissue matrices from fish skin, and the material is healthy, non-toxic, and structurally sound. The business focuses on designing applications for medical devices with a projected high return on investment and a low-to-medium production cost. Using its core Omega3 fish-skin technology, Kerecis focuses exclusively on tissue regeneration and maintenance.

Conclusion

In the internationally expanding cellular therapy and infection prevention industries, Kerecis is a leader in the use of fish skin and fatty acids. The topical and oral fatty-acid formulations of Kerecis protect the body from bacterial and viral infections.